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Bio-UnaGrid: Easing Bioinformatics Workflow Execution Using LONI Pipeline and a Virtual Desktop Grid

Authors:
Mario Villamizar
Harold Castro
David Mendez
Silvia Restrepo
Luis Rodriguez

Keywords: Bio-UnaGrid; grid computing; cluster computing; bioinformatics; BLAST; mpiBLAST; desktop grid; UnaGrid; LONI Pipeline

Abstract:
Bioinformatics researches use applications that require large computational capabilities regularly provided by cluster and grid computing infrastructures. Researchers must learn tens of commands to execute bioinformatics applications, to coordinate the manual workflow execution and to use complex distributed computing infrastructures, spending much of their time in technical issues of applications and distributed computing infrastructures. We propose the Bio-UnaGrid infrastructure to facilitate the automatic execution of intensive-computing workflows that require the use of existing application suites and distributed computing infrastructures. With Bio-UnaGrid, bioinformatics workflows are easily created and executed, with a simple click and in a transparent manner, on different cluster and grid computing infrastructures (line command is not used). To provide more processing capabilities, at low cost, Bio-UnaGrid use the idle processing capabilities of computer labs with Windows, Linux and Mac desktop computers, using a key virtualization strategy. We implement Bio-UnaGrid in a dedicated cluster and a computer lab. Results of performance tests evidence the gain obtained by our researchers.

Pages: 12 to 19

Copyright: Copyright (c) IARIA, 2011

Publication date: May 22, 2011

Published in: conference

ISSN: 2308-4383

ISBN: 978-1-61208-137-3

Location: Venice/Mestre, Italy

Dates: from May 22, 2011 to May 27, 2011