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Modeling Patterns of microRNA:mRNA Regulation Through Utilization of Cryptographic Algorithms

Authors:
Harry Shaw

Keywords: miRNA, mRNA; secondary structure; RSA algorithm; cryptography; hash code

Abstract:
The properties of microRNA mediated messenger RNA regulation (miRNA:mRNA) of expression are explored by use of an experimental cryptographic representation of miRNA and mRNA structures. The cryptographic approach allows differentiation of identical miRNA:mRNA bonding sequences. Hamming coding, Huffman coding and Rivest, Shamir, Adleman (RSA) encryption techniques are incorporated in the modeling process. Regulation is evaluated as a function of vector projections of mRNA sequences onto a miRNA. The model has a calibration function based upon the use of vector projections onto miRNA complementary and anti-complimentary sequences.

Pages: 48 to 54

Copyright: Copyright (c) The Government of USA, 2013. Used by permission to IARIA.

Publication date: March 24, 2013

Published in: conference

ISSN: 2308-4383

ISBN: 978-1-61208-260-8

Location: Lisbon, Portugal

Dates: from March 24, 2013 to March 29, 2013