Home // BRAININFO 2023, The Eighth International Conference on Neuroscience and Cognitive Brain Information // View article

Study on the Relationship Between Postprandial Brain Function Decline and Blood Glucose Levels

Authors:
Yuichi Sato
Yudai Ishikawa
Gaochao Cui
Kosuke Nagano
Fumiya Kinoshita
Hideaki Touyama

Keywords: Post-Lunch Dip (PLD); Event-Related Potential (ERP); P300; Contingent Negative Variation (CNV); Blood Glucose Level.

Abstract:
Post-lunch drowsiness, also known as Post-Lunch Dip (PLD), is a symptom of impaired brain function. Currently, the hypothesis that PLD is caused by an increase in post-prandial blood glucose level is supported as a possible explanation for the mechanism of PLD. However, few studies have examined the relationship between post-prandial brain dysfunction and blood glucose levels by measuring both simultaneously. In this study, we measured blood glucose levels and Event-Related Potential (ERP) before and after consumption of two foods with different carbohydrate contents, and examined the relation-ship between postprandial blood glucose fluctuations and PLD. In the high-sugar food ingestion group, two slices of bread and water were given, and the low-sugar ingestion group received low-carbohydrate bread and water. The results showed that the high-sugar food ingestion group had increased sleepiness, prolonged P300 latency, and increased early and late contingent negative variation amplitudes at 40 minutes postprandial ingestion. There were no significant differences in sleepiness, brain function, or blood glucose levels in the low-sugar ingestion group. In contrast, there was a significant increase in blood glucose levels immediately and 40 minutes after eating in the high-sugar food ingestion group resulting in brain function impairment. Therefore, it is suggested the postprandial increase in blood glucose level is related to the development of PLD. In addition, the blood glucose levels at 40 minutes after eating in the high-sugar food ingestion group were significantly lower after ERP measurement than before ERP measurement. This suggests PLD occurs during hyperglycemia" and "when blood glucose levels fall.

Pages: 1 to 7

Copyright: Copyright (c) IARIA, 2023

Publication date: March 13, 2023

Published in: conference

ISSN: 2519-8653

ISBN: 978-1-68558-067-4

Location: Barcelona, Spain

Dates: from March 13, 2023 to March 17, 2023