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Enhancing Hebbian Learning in Biological Neural Cultures Through Electrical Stimulation

Authors:
Víctor Lorente
Jose Manuel Ferrández
Eduardo Fernández
Félix de la Paz

Keywords: Cultured neural networks; Hebbian Law; induced plasticity; learning.

Abstract:
Electric stimulation has been widely used to induce changes in neuronal cultures coupled to microelectrode arrays (MEAs). In this paper, we used low-frequency current stimulation on dissociated cultures of hippocampal cells to study how neuronal cultures could be trained with this kind of stimulation. We show that persistent and synchronous stimulation of adjacent electrodes may be used for creating adjacent physical or logical connections in the connectivity graph following Hebb’s Law.

Pages: 20 to 25

Copyright: Copyright (c) IARIA, 2013

Publication date: May 27, 2013

Published in: conference

ISSN: 2308-3735

ISBN: 978-1-61208-272-1

Location: Valencia, Spain

Dates: from May 27, 2013 to June 1, 2013