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Study of Protein Conjugation with Different Types of CdTe Quantum Dots

Authors:
Jana Chomoucka
Jana Drbohlavova
Marketa Vaculovicova
Petra Businova
Jan Prasek
Jan Pekarek
Jaromir Hubalek

Keywords: quantum dots; conjugation; protein; bovine serum albumin; glutathione; 3-mercaptoacetic acid; thioglycolic acid

Abstract:
In this paper, the interaction between bovine serum albumin (BSA) and water soluble CdTe quantum dots (QDs) modified with different ligands (3-mercaptoacetic acid, thioglycolic acid and glutathione) was studied using the fluorescence spectroscopy. It was found that the presence of QDs led to a strong quenching effect of BSA, which could be explained by a covalent interaction between the protein and the quencher, demonstrating the formation of QDs-BSA bioconjugates.

Pages: 18 to 22

Copyright: Copyright (c) IARIA, 2013

Publication date: August 25, 2013

Published in: conference

ISSN: 2308-3530

ISBN: 978-1-61208-303-2

Location: Barcelona, Spain

Dates: from August 25, 2013 to August 31, 2013