Home // International Journal On Advances in Life Sciences, volume 13, numbers 1 and 2, 2021 // View article

New Way and Sensor Device for Investigation of Biosamples and Health Status of Humans and Animals

Authors:
Tatiana Kuchmenko
Anastasiia Shuba
Ruslan Umarkhanov
Darya Menzhulina
Anton Chernitskiy

Keywords: sensor; electronic nose; visualization; volatile compounds; metabolism; noninvasive diagnostic; skin; biofluid

Abstract:
This paper discusses an application of a portable electronic nose based on an array consisting of 8 piezoelectric sensors with nanostructured solid-state coatings to detect volatile biomolecules secreted by nasal mucus and skin. A fundamentally new approach is proposed for a quick assessment of the status of the human body as a whole (normal, stress, inflammation) and the work of individual systems (reproductive, endocrine, digestive). This approach includes processing the output curves of sensors to assess of the qualitative and quantitative composition of the gas mixture of biomolecules secreted by the skin in the Zakharyin-Ged zone. Two algorithms for visualizing signals from an array of sensors are proposed. The first algorithm allows constructing the four “visual prints”, reflecting the state of the human body (general, endocrine, energy, negative). The second algorithm constructs the health status sphere, which specifies the possible causes of deviation in health. Also, a portable electronic nose was applied in the veterinary field to assess the health status of calves’ respiratory system. Unlike the traditional approach in diagnostics using a sensor array, one sample of nasal mucus was monitored for 5-9 hours with an interval of 2-3 hours. The new parameter is proposed to separate the diagnostic group of calves according to respiratory tract health. The changes in the composition of the gaseous phase over nasal mucus samples were considered. Using an electronic nose with nanostructured piezoelectric sensors, the speed and simplicity of measurement allow painlessly scanning the body for metabolic disturbances and estimating certain pathologies' presence and treatment effectiveness. The proposed algorithms and device for analysis of biosamples from humans and animals could be implemented to rapidly diagnose health status on farms, hospitals, and at home.

Pages: 1 to 13

Copyright: Copyright (c) to authors, 2021. Used with permission.

Publication date: December 31, 2021

Published in: journal

ISSN: 1942-2660