Home // International Journal On Advances in Life Sciences, volume 16, numbers 1 and 2, 2024 // View article

Assessment of Pharmacology Costs in Diabetes Treatment Using OMOP CDM: A Nationally Representative Study

Authors:
Evgeniy Krastev
Petko Kovachev
Simeon Abanos
Ralitsa Krasteva
Dimitar Tcharaktchiev

Keywords: diabetes mellitus; diabetes register; nationally representative study; registry; database; OMOP CDM; Common Data Model; pharmacology; cost analysis

Abstract:
Public diabetes reports rarely use large volume of observational health data because these data are usually heterogenous in terms of structure and semantic presentation of clinical concepts. In this paper we employ observational health data transformed to OMOP CDM database in a nationally representative study with the goal to estimate the pharmacology costs for diabetes treatment in Bulgaria during 2018. The OMOP CDM database contains health data from pseudonymized outpatient records of 501,065 patients with diabetes (45.3% male and 54.7% female). The mean age of the patients with Type 1 (42.249 patients) and Type 2 (458.816 patients) gives mean age 57.04 (CI 95%, [56.87, 57.22]) years for Type 1 and 66.38 (CI 95%, [66.35, 66.41]) years for Type 2. Drug costs are evaluated with respect to the major classes of drugs prescribed for diabetes treatment and diabetes comorbidities treatment. The annual average cost of drugs per patient with diabetes is estimated to 750 Euros. The obtained results are new and help to understand the trends and effects in using different classes of drugs for diabetes treatment. Novel drug diabetes therapies are found to be evolving in 2018, while the Metformin prescriptions prevail significantly. The costs in this study we evaluate both at patient-centric level by age groups and gender specifics and at high level in terms of cost distributions among the drug classes in each group. The results are graphically visualized, discussed, and compared in relation to existing public sources.

Pages: 11 to 20

Copyright: Copyright (c) to authors, 2024. Used with permission.

Publication date: June 30, 2024

Published in: journal

ISSN: 1942-2660