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Self-Assembled Plasmonic Sensor Platforms: a Promising Approach for Monitoring Enzymatic Degradation of Thin Gelatin Layers

Authors:
Markus Weiler
Stefan B. Quint
Supratim Basak
Claudia Pacholski

Keywords: Optical sensor; bottom-up; enzymes; surface plasmon resonance; real-time monitoring

Abstract:
Plasmonic sensors based on periodic hole arrays in metallic films are investigated for monitoring enzymatic degradation of extracellular matrix. Sensors are fabricated using a bottom-up strategy in which soft colloidal lithography is combined with chemical gold film deposition. The resulting plasmonic sensors show extraordinary transmission of light supported by surface plasmon polaritons. These are highly sensitive to refractive index changes in close proximity to the sensor surface and are utilized for the quantitative detection of extracellular matrix degradation.

Pages: 108 to 113

Copyright: Copyright (c) IARIA, 2018

Publication date: September 16, 2018

Published in: conference

ISSN: 2308-3514

ISBN: 978-1-61208-660-6

Location: Venice, Italy

Dates: from September 16, 2018 to September 20, 2018