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Signal Accuracy of Terahertz Chemical Microscope for Lung Cancer Cell Detection

Authors:
Yuichi Yoshida
Xue Ding
Kohei Iwatsuki
Sayaka Tsuji
Hirofumi Inoue
Jin Wang
Kenji Sakai
Toshihiko Kiwa

Keywords: terahertz chemical microscope; terahertz; immobilizing antibody; cancer cell

Abstract:
It is essential to evaluate the number of cancer cells to analyze cancer genome for cancer genomic medicine. However, it takes a long time, and pathologists’ skills are needed to evaluate it. Our group has developed and proposed a Terahertz Chemical Microscope (TCM) to evaluate it easily and fast. In this study, antibodies were immobilized by covalent bonding and avidin-biotin reaction to detect cancer cells, and their immobilizing methods were compared. The results suggest that signal accuracy is improved to detect lung cancer cells using avidin-biotin reaction.

Pages: 82 to 83

Copyright: Copyright (c) IARIA, 2021

Publication date: November 14, 2021

Published in: conference

ISSN: 2308-3514

ISBN: 978-1-61208-918-8

Location: Athens, Greece

Dates: from November 14, 2021 to November 18, 2021