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Detection of Proteins Associated with Alzheimer’s Disease using a Terahertz Chemical Microscope

Authors:
Kohei Iwatsuki
Yuichi Yoshida
Xue Ding
Sayaka Tsuji
Jin Wang
Kenji Sakai
Toshihiko Kiwa

Keywords: Terahertz; TCM; Alzheimer’s Disease; mild cognitive impairment

Abstract:
In recent years, the number of Alzheimer’s Disease (AD) has been increasing. We proposed a Terahertz Chemical Microscope (TCM) for early diagnosis of cognitive decline by measuring the concentration of Apolipoprotein AⅠ (ApoA1) and Complement component 3 (C3) in solution as biomarkers for AD using the TCM. As a results, ApoA1 and C3 with the concentration of 0.1 µg/ml and 1.0 µg/ml could be respectively detected by measuring the change in the amplitude of terahertz waves by the TCM.

Pages: 84 to 85

Copyright: Copyright (c) IARIA, 2021

Publication date: November 14, 2021

Published in: conference

ISSN: 2308-3514

ISBN: 978-1-61208-918-8

Location: Athens, Greece

Dates: from November 14, 2021 to November 18, 2021