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Comparison of corneal pulse entropy to distinguish healthy eyes from those with primary open-angle glaucoma

Authors:
Michał M. Placek
Patryk M. Ząbkiewicz
Monika E. Danielewska

Keywords: multiscale entropy; corneal pulsation; glaucoma diagnosis

Abstract:
Corneal Pulsation (CP), as one of the manifestations of eye dynamics, has shown a great potential in the glaucoma diagnosis. The morphology of the CP signal, acquired noninvasively with a non-contact ultrasonic technique, has been found to alter in glaucoma patients. The aim of this preliminary study was to ascertain whether complexity of the CP signal may be a useful parameter to differentiate glaucoma patients from healthy individuals. Refined Composite Multiscale Fuzzy Entropy (RCMFE) was considered as a complexity measure. RCMFE of the CP signal was calculated in 25 glaucoma patients and 25 healthy subjects. Statistical analysis showed that, on average, glaucomatous eyes were characterized by higher entropy of the CP signal than healthy ones. This result suggests that RCMFE of the CP signal may support ophthalmologists in glaucoma diagnosis in its early stages.

Pages: 29 to 30

Copyright: Copyright (c) IARIA, 2019

Publication date: June 2, 2019

Published in: conference

ISSN: 2519-8432

ISBN: 978-1-61208-716-0

Location: Athens, Greece

Dates: from June 2, 2019 to June 6, 2019