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An Integrative Strategy for Solving the EEG Inverse Problem and the Estimation of Brain Effective Connectivity in Epilepsy. A Proof-of-Concept Study.

Authors:
Marc Greige
Ahmad Karfoul
Pascal Benquet
Maxime Yochum
Régine Le Bouquin Jeannès

Keywords: Effective connectivity; inverse problem; optimization; EEG; epilepsy.

Abstract:
This study presents an integrative strategy for simultaneously localizing brain sources and inferring effective connectivity. The proposed approach leverages the model underlying the events of interest as a regularizer in the electroencephalographic inverse problem. The effectiveness of this strategy is confirmed using realistic simulated high resolution electroencephalographic signals in the context of epilepsy, and compared to the conventional sequential strategy, where connectivity estimation is performed after solving the electroencephalographic inverse problem.

Pages: 8 to 10

Copyright: Copyright (c) IARIA, 2025

Publication date: March 9, 2025

Published in: conference

ISSN: 2519-8432

ISBN: 978-1-68558-245-6

Location: Lisbon, Portugal

Dates: from March 9, 2025 to March 13, 2025