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Smartphone-based Optical System for Blood Coagulation Self-monitoring

Authors:
Ramji Sitaraman Lakshmanan
Vitaly Efremov

Keywords: blood coagulation; nephelometry; clotting time; light scattering; smartphone

Abstract:
Blood coagulation self-monitoring is vital in modern day healthcare, in particular supporting patients on anticoagulant therapy. Commercially-available coagulation self-monitoring devices are typically based on conventional end-point-based haemostatic tests and, measuring clotting time within a narrow range of values being connected to specific aspects of clot formation. In the present study, novel optical method combined with a smartphone was applied to measure the clotting time. The method was utilised for analysis of normal whole blood (WB) sample coagulation, activated by various tissue factor (TF) concentrations. The results demonstrated the ability of such a system to measure a wide range of clotting time values with appropriate level of accuracy and precision similar to standard thromboelastography (TEG). Significantly, the use of a smartphone as an optical detector and signal processor potentiates system miniaturisation, pertinent to high levels of functionality, cost-efficiency and user-friendliness.

Pages: 251 to 256

Copyright: Copyright (c) IARIA, 2016

Publication date: April 24, 2016

Published in: conference

ISSN: 2308-4359

ISBN: 978-1-61208-470-1

Location: Venice, Italy

Dates: from April 24, 2016 to April 28, 2016